The South Dakota Health Research Foundation occupies lab space in two facilities.

The first space, located in the lower level of the University Of South Dakota School Of Medicine, Health Sciences Center has approximately 3000 sq. feet. The space includes three large shared labs, a multi-purpose room, imaging room, tissue culture room, conference room, shared technical staff/student office, 6 private faculty offices, and an administrative office suite. An adjacent 2000 sq. foot area is ready to be built out, should space needs warrant.

Equipment at this site includes:

• Millipore Water Purifier
• Beckman Coulter Avanti J-30i Centrifuge
• Beckman Optima Tabletop Ultracentrifuge
• BioRad MyiQ Real Time PCR (USDSM)
• Coulter Channelizer
• Criterion Cell/Plate Blotter
• Ultrospec 2100pro Plum spectrophotometer
• 6' Baker SterilGardII Biosafety Cabinet

The second SDHRF facility occupies much of the seventh floor of the Avera Doctor's Plaza 2. This locale offers approximately 12,500 sq. feet of research space. It includes two conference rooms (324 and 200 sq. feet), primary and secondary cell culture labs (80 and 238 sq. feet), virus culture lab (112 sq. feet), imaging lab (143 sq. feet), gel documentation room (88 sq. feet), shared equipment room (88 sq. feet), dark room (60 sq. feet), isotope lab (80 sq. feet), and autoclaving/prep room (80 sq. feet). Individual investigators occupy five labs that are approximately 450 sq. foot each and two larger lab suites of 994 sq. feet and 1104 sq. feet.

Major equipment at this site includes:

• Applied Biosystems Voyager-DE MALDI-TOF Mass Spectrometer
• Applied Biosystems Vision Chromatography Workstation
• Applied Biosystems RT-PCR
• Perkin Elmer LS Luminescence Spectrophotometer
• BioRad Molecular Imager FX and Model 3000 Versadoc Gel Imaging System
• Beckman J2-MC High Speed Centrifuge
• Beckman XL-80 Ultracentrifuge
• Beckman LS 6500 Liquid Scintillation Counter
• Perkin Elmer Fusion Plate Reader
• Olympus Fluoview Confocal Scanning Microscope (with krypton/argon lasers)
• Nikon Eclipse TE2000S Fluorescence Microscope with LiveCell Chamber
• Olympus IX71 Fluorescence Microscope
• Zeiss Axioplan Microscope (with video camera image analysis)
• Olympus BHS Epifluorescence Microscope (with image analysis system)
• VisualSonics Vevo 660 Ultrasound System
• Amsco 3021 Autoclave

The following cores have been developed to facilitate research within the Foundation and in conjunction with The University of South Dakota School of Medicine and Health Sciences, Department of Basic Biomedical Sciences:

• Cell Culture Core- Dr. Tim. O'Connell, Director
• Cell Biology and Imaging Core- Dr. Stephen Armstrong, Director
• Molecular Biology Core- Dr. Qiangrong Liang, Director
• Physiology Testing Core- Dr. Martin Gerdes, Director
• Flow Cytometry Core- Dr. Carlos Telleria, Director
• Protein Characterization Core- Dr. Benjamin Perryman, Director