Sanford Research/USD

Kristi A Egland, PhD (University of Iowa)

Junior Scientist, Signal Transduction Institute, Oncology Research Institute
Assistant Professor, Dept. of Ob/Gyn. and Dept. of Lab Medicine,
The University of South Dakota School of Medicine and Health Sciences
(605) 357-1491

kegland@usd.edu

Education

2000 – Ph.D. in Molecular Biology, University of Iowa, Iowa City, IA
Thesis Mentor: Dr. E. Peter Greenberg
Thesis Title: Mechanism of quorum sensing: transcriptional activation of the luminescence genes by LuxR.
1992 – Bachelor of Arts, Washington University, St. Louis, MO

Research and Professional Experience

Sept. 2004 Research Scientist, South Dakota Health Research Foundation, Sioux Falls, SD
Sept. 2004 Assistant Professor, University of South Dakota School of Medicine and Health Sciences
2000-2004 Post-doctoral Fellow in the Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD Dr. Ira Pastan, Laboratory Chief
1993-1999 Graduate Student in the Department of Microbiology, University of Iowa Dr. E. Peter Greenberg, Laboratory Chief

Distinctions

Pharmacology Research Associate Training (PRAT) Program Fellowship, NIGMS, NIH
2001-2003 Technology Transfer Award, CCR, NCI, NIH
2000-2001 Cancer Research Training Award, NCI, NIH
1995-1997 NIH Training Grant in Biotechnology, University of Iowa
1994-1995 Center for Biocatalysis & Bioprocessing Fellowship, University of Iowa

Research Focus

Identifying specific breast cancer proteins for use as targets of immunotoxin therapy.

Publications

1. Egland, K.A., Vincent, J.J., Strausberg, R., Lee, B.K. and Pastan, I.: Discovery of the breast cancer gene BASE using a molecular approach to enrich for genes encoding membrane and secreted proteins. Proc. Natl. Acad. Sci. USA 100: 1099-1104, 2003.
2. Egland, K.A., Kumar, V., Duray, P. and Pastan, I.: Characterization of overlapping XAGE-1 transcripts encoding a cancer testis antigen expressed in lung, breast, and other types of cancers. Mol. Cancer Ther. 1: 441-450, 2002.
3. Egland, K.A., Kumar, V., Duray, P. and Pastan, I.: Cover photograph. Mol. Cancer Ther. 1, 2002.
4. Egland, K.A. and Greenberg, E.P.: Quorum sensing in Vibrio fischeri: analysis of the LuxR DNA binding region by alanine-scanning mutagenesis. J. Bacteriol. 183: 382-386, 2001.