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Maria C Bell, MD (University of South Dakota)

Scientist, Oncology Research Institute
Professor, Dept. of Ob/Gyn, Sanford School of Medicine, Sioux Falls, SD (605) 328-7700

bellm@siouxvalley.org

    Education
  • B.A. – Biology/Chemistry, Augustana College, Sioux Falls, SD Sept. 1980-May 1984
  • M.D. – University of South Dakota School of Medicine and Health Sciences, Sioux Falls, SD May 1984-May 1988
  • Ob/Gyn Internship – St. Joseph's Hospital, Chicago, IL, July 1988-June 1989
  • Residency Ob/Gyn – University of Chicago Hospital, Chicago, IL, July 1989-June 1992
  • Fellowship Gyn/Onc – University of Alabama at Birmingham, Birmingham, AL July 1992-June 1995
  • Pending MPH – Johns Hopkins Bloomberg School of Public Health, Baltimore, MD,
    Certifications
  • National Board of Medical Examiners - diplomate 7/1/99
    Part I - passed 6/86
    Part II -passed 9/87
    Part III- passed 6/89
  • Diplomate American Board of Obstetrics and Gynecology #JFP0363342 (11/96)
  • Diplomate Division of Gynecologic Oncology (March, 1999)
    Experience
  • Scientist, Sanford Research/USD, 2003-current
  • Gynecological Oncologist, Sioux Valley Clinic Ob/Gyn Ltd. 2000-current
  • Professor, Dept. of Ob/Gyn, Sanford School of Medicine 2006-current
  • Associate Professor, Sanford School of Medicine 2000-2006
  • Chairman Cancer Committee, Sioux Valley Hospital- May 2002-current
  • Cancer Advisory Committee, Sioux Valley Hospital- January 2002-current
  • American Cancer Society Advisory Board - June 2002-current
  • All Women Count Medical Director - January 2002-current
  • Commission on Cancer State Chair for South Dakota - July 2002-current
  • Cancer Liaison Physician, Sioux Valley Hospital - July 2002-current
  • Fourth year Clerkship Director of Ob/Gyn, Sanford School of Medicine - July 2002-current
  • Reviewer for Gynecologic Oncology 2002-current
  • Reviewer for the International Journal of Gynecologic Cancer 2002-current
  • Assistant Professor, Department Ob/Gyn University of Colorado Health Sciences Center August 1999-March 2000
  • Assistant Professor, Department Ob/Gyn, Director of Gynecologic Oncology LSUMC Shreveport, July 1995-July 1999
    Professional Societies
  • American College of Obstetricians and Gynecologists (fellow) Sept 1997-current
  • International College of Surgeons (fellow) 1995
  • Society of Gynecologic Oncology (fellow) 1996-current
  • American College of Surgeons (fellow) October 1998-current
  • American Society of Clinical Oncologists 1996-current
  • Association of Professors of Gynecology and Obstetrics 1996-current
  • Association of Women Surgeons 1998
  • Medicine for Humanity 1999-current
  • SD Women’s Cancer Network 1999-current
  • International Healthcare Development Foundation 2003-current
    Research Focus
  • Gynecological Oncology Group
  • North Central Cancer Treatment Group
  • Southwest Oncology Group
  • American Cancer Society grant - HPV analysis on the Rosebud Indian Reservation - $25,000 August 2001-July 2002
  • Spirit of Eagles grant, sub-recipient of Mayo - HPV and cervical immunology assessment in women on Rosebud and Pine Ridge Indian Reservations. - $50,000 April 2003-March 2004 (NIH)
  • Eggers grant- Interaction of HPV and Hormones. $10,000, July 2003-June 2004
  • Ovarian cancer, Cervical Cancer
    Publications
  • Nauman RW, Bell MC, Alvarez RD, Edwards RP, Partridge EE, Helm CW, Shingleton HM. McGee JA, Higgins RV, Hall JB.  LLETZ is an acceptable alternative to diagnostic cold-knife conization.  Gynecol Oncol, 55(2), pp 224-228, Nov. 1994.

    Bell MC, Edwards RP, Crowley-Norwick PA, Partridge EE:  CD8+ lymphocytes are recruited to the dysplastic cervix.  J Clin Immun, Vol. 15, No. 3, pp 130-136, May 1995.     

    Bell MC, Alvarez R, Connor M.  Squamous cell carcinoma arising in an immature teratoma of the cervix in an HIV positive patient – a case report. Gynecol Oncol, Vol. 60, pp 475-479, 1996.

    Lai P, Rabinowich H, Crowley-Nowick PA, Bell MC, Mantovani G, Whiteside T.  Alterations in expression and function of signal transducing proteins in tumor-associated T and Natural Killer cells in patients with ovarian carcinoma. Clinical Cancer Research ,Vol. 2, pp 161-173.

    Bell MC and Partridge EE.  Early breast carcinoma:  overview of risk factors, screening, and treatment. Contemporary OB/GYN, pp 31-51, Dec. 1995.

    Shingleton HW, Bell MC, Fremgen A, Jones WB, Russell AH, Oewieja K, Winchester D, Clive R, Chmiel J.  Is there really a difference in survival of women with early stage squamous cell carcinoma, adenocarcinoma, and adenosquamous cell carcinoma of the cervix? Cancer, Vol. 76, No. 10, pp 1948-1955, Nov. 15, 1995.

    Crowley-Nowick PA, Bell, MC, Edwards R, McCallister D, Gore H, Kanbour-Shakir A, Mestecky J, Partridge E.  Normal Uterine Cervix:  Characterization of Isolated Lymphocyte Phenotypes and Immunoglobulin Secretion. American Journal of Reproductive Immunology, (34), pp 241-247, Oct.1995.

    Rabinowich H, Suminami Y, Reichert T, Crowley-Nowick PA, Bell MC, Edwards R, Whiteside T.  Expression of cytokine genes or proteins and signaling molecules in lymphocytes associated with human ovarian cancer. Int. J. Cancer, (68), pp 276-284, 1996.

    Lai P, Rabinowich H, Crowley-Nowick PA, Bell MC, Mantovani G, Whiteside T.  Alterations in Expression and Function of Signal-transducing Proteins in Tumor-associated T and Natural Killer Cells in Patients with Ovarian Carcinoma.  Clinical Cancer Research, Vol. 2, pp 161-172, Jan. 1996.

    VonZons P, Crowley-Nowick PA, Friberg D, Bell MC, Koldovsky U, Whiteside T.  Comparison of europium and chromium release assays:  Cytotoxicity in healthy individuals and patients with cervical carcinoma.  Clinical and Diagnostic Laboratory Immunology, pp 202-207, Mar. 1997.

    Corwley-Nowick PA, Bell MC, Brockwell R, Edwards RP, Chen S, Partridge EE, Mestecky J.  Rectal Immunization for Induction of Specific Antibody in the Genital tract of Women:  J Clin Immunol, Vol. 17, No. 5, pp 370-379, 1997.

    Ampil FL,  Bell MC, Martin D.  Reappearance of cancer of the cervix 19 years after radiotherapy:  Acta Obstet Gynecol Scan, 76, pp 605-606, 1997.

    Ampil FL, Bell MC, Meyers P.  CT-Detected Hydrometra Before Irradiation for Cancer of the Cervix:  Eur J Gynecol Oncol, Vol. 18, pp 368-370, 1997.

    Lai P, Ravinowich H, Crowley-Nowick PA, Bell MC , Mantovani G, Whiteside TL.   Alterations of expression and function of signal transducing proteins in tumor-associated T and natural killer cells in ovarian carcinoma.  Biochem Soc Trans, 25(2):218S, 1997.

    Ampil FL and Bell MC.  Brachytherapy in the presence of pyuria after irradiation for cervical cancer:  Eur J of Gyn. Onc., Vol 19, pp 350-351, Sept. 1998.

    Rabinowich H, Reichert TE, Kashi Y, Gastman BR, Bell MC, Whiteside TL.   Lymphocyte apoptosis induced by Fas ligand-expressing ovarian carcinoma cells.  J. Clin. Invest., Vol. 101, No. 11, pp 2579-2588, June 1998.

    Ampil FL and Bell MC.  Aggressive radiotherapy for stage IIIB cancer of the cervix: Helpful or Harmful?  Acta Obstet Gynecol Scand, 77, p 359, 1998.

    Ampil FL, Apple S, Bell MC.  Spinal epidural compression complicating cancer of the cervix:  review of seven cases.  Eur J Gynecol Oncol, 19(2), pp 105-107, 1998.

    Maihles JB, Carabatsos MJ, Young D, London SN, Bell MC, Albertini DF.  Taxol-induced meiotic maturation delay, spindle defects, and aneuploidy in mouse oocytes and zygotes.  Mutation Research, Vol. 423, pp 79-90, 1999.

    Ampil FL and Bell MC.  Pelvis Malignancy in female nonagenarians.  Eur J Gynecol Oncol, 20(2), pp 102-104, 1999.

    Bell MC, Schmidt-Grimminger D, Turbat-Herrera E, Tucker A, Harkins L, Prentice N, Crowley-Nowick PA.  HIV+ Patients have increased lymphocyte infiltrates in CIN lesions.  Gynecol Oncol, Vol. 76, pp 315-519, 2000.

    Bell MC, Crowley-Nowick PA, Bradlow HL, Sepkovic DW, Schmidt-Grimminger DC, Howell P, Mayeaux EJ, Tucker A, Turbat-Herrera EA, Mathis JM.  Placebo-controlled trial of Indole-3-carbinol in the treatment of cervical dysplasia. Gynecol Oncol, 78, pp 123-129, 2000.

    Bell MC, Davidson SA, Mathis JM, Ampil FL.  Topotecan Concomitant with Primary Radiation in patients with cervical carcinoma, A Phase I Trial.  Gynecol Oncol, 80(2), pp 128-131, 2001.

    Follen M, Meyskens FL Jr, Alvarez RD, Walker JL, Bell MC, Storthz KA, Sastry J, Roy K, Richards-Kortum R, Cornelison TL.  Cervical cancer chemoprevention, vaccines, and surrogate endpoint biomarkers.  Cancer, Nov .1, p 98 (9 Suppl), pp 20044-20051, 2003.

    Timble EL, Bell MC, Wolf J, Alvarez R.  Grantsmanship and Career Development for Gynecologic Cancer Investigators.  Cancer, Nov. 1, p 98 (9 Suppl), pp 2075-2081, 2003.

    Bell MC amd Alvarez RD.  Chemoprevention and vaccines: a review of the nonsurgical options for the treatment of cervical dysplsia.  Int J Gynecol Cancer, 15(1), pp 4-12, 2005.
  • Book Chapters:
    Carroll, JL, Mathis JM, Bell MC, Santoso JT. “p53 adenovirous as gene therapy for ovarian cancer”. Methods and Molecular Medicine: Ovarian Cancer, Humana Press, Tanaka, NJ (1998) In press.
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